This year, American riders will race full time in all three classes for the first time since 1990, including at Indy.
2006 MotoGP World Champion Nicky Hayden and Colin Edwards will represent the United States in the premier MotoGP class, while Stevie Bonsey climbs to the 250cc class. Cameron Beaubier will ride as a rookie in 125cc.
Inaugural Red Bull Indianapolis GP runner-up Hayden made a high-profile switch to the Ducati Team to join 2007 World Champion Casey Stoner after last season. Edwards remains with Tech 3 Yamaha.
Six-time MotoGP World Champion Valentino Rossi will defend his Red Bull Indianapolis GP title with the Fiat Yamaha Team.
The Red Bull Indianapolis GP will be the third motor race of the track's Centennial Era, a three-year celebration honoring the 100th anniversaries of the opening of the famed facility in 1909 and the inaugural Indianapolis 500 in 1911.