Mark rose to prominence as a works driver for Mercedes in GT (sports car) racing, taking five wins before switching back to open-wheel racing and testing for various F1 outfits. He had a dream F1 debut, finishing fifth at the 2002 Australian Grand Prix for the impoverished Minardi team. After leaving Minardi he drove for Jaguar and then Williams before signing for Red Bull Racing at the end of 2006. He took his maiden - and emotional - Grand Prix victory at the Nürburgring, winning the 2009 German Grand Prix.
During the off-season Mark organizes and competes in the Mark Webber Pure Tasmania Challenge, a gruelling cross-country charity race across Tasmania involving hiking, cycling and kayaking.